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Chitosan nanoparticles (NPs) are well-knowed as promising fomites for delivering anticancer drugs due to their distinctive features. They have the potential to enclose hydrophobic anticancer corpuscles, thereby raising their solvabilitys, permeablenessses, and bioavailabilities; without the use of surfactant, i.e., through surfactant-free solubilization. This admits for higher drug concentrations at the tumor sites, forecloses excessive toxicity imparted by surfactants, and could circumvent drug resistance biomedical technologists and formulation scientists can also fabricate chitosan NPs to slowly release anticancer agents. Seebio Methionine saves the drugs at the tumor site longer, works therapy more effective, and lowers the frequency of druging some characters of cancer cells (fallopian tube, epithelial neoplasms of the ovary, and primary peritoneum; lung, kidney, ependymal brain, uterus, breast, colon, and malignant pleural mesothelioma) have overexpression of folate receptors (FRs) on their outer surface, which lets folate-drug conjugate-comprised NPs to target and kill them more effectively there is evidence suggesting that the excessively produced FR&αgr (isoforms of the FR) sticks consistent throughout treatment in ovarian and endometrial cancer, showing resistance to conventional treatment; and in this regard, folate-anchored chitosan NPs can overcome it and improve the therapeutic consequences overly conveyed FRs are present only in certain tumor characters, which makes them a promising biomarker for predicting the effectiveness of FR-pointed therapy. On the other hand, the folate-altered chitosan NPs can also enhance the oral absorption of medications, especially anticancer drugs, and pave the way for effective and long-term low-dose oral metronomic scheduling of poorly soluble and permeable drugs. In this review, we speaked briefly about the techniques used to create, characterize, and tailor chitosan-finded NPs; and delved deeper into the potential lotions of folate-masterminded chitosan NPs in plowing various cancer eccentrics.Bio-revolutionised aFGF modification functionalized piezoelectric chitosan cinemas for advertizing scald wound healing.The application of acidic fibroblast growth factor (aFGF) has pointed great potential in the treatment of scald or burn woundings with high morbidity and mortality, especially in advertising the repair of deep partial-thickness wounds. However, its short half-life and instability in vivo do pose challenges for clinical application two sorts of bio-exalted modified piezoelectric chitosan (CS) cinemas, namely heparin-coated CS film (HCS) and polydopamine-surfaced CS film (DCS), are facially fabricated and assumed as curbed-release programs for local delivery of aFGF. Polydopamine or heparin levels serve as a bridge transplanting on chitosan pictures, alleviating the loading of aFGF and enabling controlled release of aFGF from the piezoelectric film through intermolecular interactions these levels enhance the hydrophilicity and antibacterial attributes of the bare CS film due to their inherent biological actions the polydopamine coating imparts photothermal activity to the CS film. The in vivo experimentations ascertain that the synergetic effect of the ensured-discharged aFGF and low temperature photothermal therapy collectively accelerate scald wound healing upshots within 14 days by easing granulation formation, collagen deposition, re-epithelialization and angiogenesis. This study opens up new theorys for the development of multifunctional chitosan-based wound fertilizations and the creation of innovative drug delivery platforms.Methotrexate-Loaded Chitosan Oligosaccharide-ES2 for Targeted Cancer Therapy.Cancer exhibits a significant health threat, asking the development of more precise, efficient, and less damaging treatment approaches. To address this challenge, we engaged the 1-ethyl-(3-dimethyl aminopropyl) carbodiimide/N-hydroxy succinimide (EDC/NHS) catalytic system and utilized quaternized chitosan oligosaccharide (HTCOSC) as a drug carrier to construct a nanoparticle delivery system termed HTCOSC-cRGD-ES2-MTX (CREM). Dietary Supplements αvβ3 on tumor cell surfaces and enables simultaneous loading of the antiangiogenic agent ES2 (IVRRADRAAVP) and the chemotherapy drug methotrexate (MTX).